Published date: 23 October 2020

Closed opportunity - This means that the contract is currently closed. The buying department may be considering suppliers that have already applied, or no suitable offers were made.



Closing: 6 November 2020, 3pm

Contract summary

Industry

  • Laboratory, optical and precision equipments (excl. glasses) - 38000000

Location of contract

TW11 0LW

Value of contract

£0

Procurement reference

tender_254646/897897

Published date

23 October 2020

Closing date

6 November 2020

Closing time

3pm

Contract start date

30 November 2020

Contract end date

1 November 2021

Contract type

Supply contract

Procedure type

Competitive quotation (non-OJEU)

The buyer selects a group of potential suppliers to invite to tender.

Non-OJEU (Official Journal of the European Union) procedures are valued below a certain financial threshold.

Contract is suitable for SMEs?

Yes

Contract is suitable for VCSEs?

No


Description

The National Physical Laboratory (NPL) requires automation to facilitate the purification of peptides which have been synthesized via 9-Fluorenylmethoxycarbonyl (Fmoc) Solid Phase Peptide Synthesis (SPPS). Due to the intrinsic nature of this synthetic technique, it is quite common to isolate crude peptides as a mixture of the desired product and closely related impurities (e.g. protecting group adducts / deletion sequences).

NPL tends to synthesize difficult peptides (self assembling, repeating motifs, slightly insoluble sequences) on 0.1 mmol scale via microwave assisted Fmoc SPPS; yielding 150 mg to 400 mg of crude product after resin cleavage. NPL is seeking to purchase a preparative HPLC, which will facilitate the purification of larger quantities of crude peptide per run (than we are currently able, i.e. >> 15-20 mg per un); and therefore yield greater quantities of highly pure peptides.


More information

Links

Additional text

Please do not contact the person listed on this notice. Documents can only be obtained through Bravo Solutions.


About the buyer

Address

Hampton Road
Teddington
TW11 0LW
England

Email

charley.choules@npl.co.uk


Closing: 6 November 2020, 3pm