Published date: 23 October 2020
Closed opportunity - This means that the contract is currently closed. The buying department may be considering suppliers that have already applied, or no suitable offers were made.
Contract summary
Industry
Laboratory, optical and precision equipments (excl. glasses) - 38000000
Location of contract
TW11 0LW
Value of contract
£0
Procurement reference
tender_254646/897897
Published date
23 October 2020
Closing date
6 November 2020
Closing time
3pm
Contract start date
30 November 2020
Contract end date
1 November 2021
Contract type
Supply contract
Procedure type
Competitive quotation (below threshold)
The buyer selects a group of potential suppliers to invite to tender.
This procedure can be used for procurements below the relevant contract value threshold.
Contract is suitable for SMEs?
Yes
Contract is suitable for VCSEs?
No
Description
The National Physical Laboratory (NPL) requires automation to facilitate the purification of peptides which have been synthesized via 9-Fluorenylmethoxycarbonyl (Fmoc) Solid Phase Peptide Synthesis (SPPS). Due to the intrinsic nature of this synthetic technique, it is quite common to isolate crude peptides as a mixture of the desired product and closely related impurities (e.g. protecting group adducts / deletion sequences).
NPL tends to synthesize difficult peptides (self assembling, repeating motifs, slightly insoluble sequences) on 0.1 mmol scale via microwave assisted Fmoc SPPS; yielding 150 mg to 400 mg of crude product after resin cleavage. NPL is seeking to purchase a preparative HPLC, which will facilitate the purification of larger quantities of crude peptide per run (than we are currently able, i.e. >> 15-20 mg per un); and therefore yield greater quantities of highly pure peptides.
More information
Links
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- https://lupc.bravosolution.co.uk/web/login.shtml
- Tender notice
- Please ensure that you register on Bravo Solutions (link below) to obtain the documents and submit your interest / intention to bid.
Additional text
-
Please do not contact the person listed on this notice. Documents can only be obtained through Bravo Solutions.
About the buyer
Address
Hampton Road
Teddington
TW11 0LW
England
Website
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Closing: 6 November 2020, 3pm