Published date: 28 August 2016

Closed opportunity - This means that the contract is currently closed. The buying department may be considering suppliers that have already applied, or no suitable offers were made.


Closing: 30 August 2016

Contract summary

Industry

  • Medical equipments, pharmaceuticals and personal care products - 33000000

  • Clinical chemistry system - 33159000

  • Pharmaceutical products - 33600000

    • Chemistry analyser - 38434560

Location of contract

South West

Value of contract

£10,000 to £113,000

Procurement reference

BIP46001046

Published date

28 August 2016

Closing date

30 August 2016

Contract start date

30 September 2016

Contract end date

31 March 2017

Contract type

Service contract

Procedure type

Open procedure

Any interested supplier may submit a tender in response to an opportunity notice.

Contract is suitable for SMEs?

No

Contract is suitable for VCSEs?

No

Description

NOTE: This notice was updated on 28 August 2016 for the following reason: Description of requirements changed to the following and requirement to be GLP compliant now removed as a pre-requisite to submitting an Expression of Interest

Dstl is developing a number of active pharmaceutical ingredients (API) as medical countermeasures. In vitro metabolism studies of three API are required as the project moves forwards. These include determination of metabolism kinetics, metabolite identification, metabolising enzyme identification, blood:plasma ratio determination and identification of efflux transporters. All requirements will need suitably qualified analytical chemistry methods to quantify the concentrations of the API being studied. Suitable controls and appropriate factors to enable in vitro in vivo extrapolation (IVIVE) of the outputs from the work will also be required. The information/data required is in support of clinical development programmes with the API and therefore must be completed to satisfactory quality standards which must be adequately demonstrated.In vitro metabolism of the API being developed by Dstl and how this will be used to improve the understanding of the drugs as the project moves forwards to clinical trials. API must be completed to Good Laboratory Practice (GLP). Only Suppliers that have the mandatory GLP systems in place should express interest in this requirement.

More information

Additional text

To view this notice, register as a supplier here:

http://www.contracts.mod.uk/delta/signup.html?userType=supplier

and search for the notice with reference 'GB-Salisbury: Pharma in vitro metabolism'.

About the buyer

Contact name

D Blackmore

Address

Commercial Services
Building 5
Salisbury
SP4 0JQ
UK

Telephone

+441980955431

Email

dblackmore@dstl.gov.uk