Microcirculatory changes during haemorrhagic shock in relation to shock and subsequent inflammatory responses

Contract summary

Industry

• Research laboratory services - 73111000

Location of contract

WC2R 2LS

Value of contract

£54,992.36

Procurement reference

1000167637

Published date

27 October 2021

Closing date

17 September 2021

Closing time

12pm

Contract start date

20 September 2021

Contract end date

31 August 2022

Contract type

Service contract

Procedure type

Call-off from a framework agreement

Contract is suitable for SMEs?

No

Contract is suitable for VCSEs?

No

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Description

The cardiovascular response to trauma (tissue injury, haemorrhagic shock and resuscitation) leads to inflammatory responses that can either cause further damage or underpin subsequent tissue healing. A novel element of the inflammatory response is the interaction between platelets and neutrophils, which have been examined in a collaborative pilot study with King's College, who have expertise in neutrophil-platelet interactions. The inflammatory response in trauma is in part orchestrated by the microcirculation. There is considerable inter-individual variation in the microcirculatory response to trauma. A detailed assessment of these responses, followed by correlation with the systemic physiological and inflammatory responses, may identify mechanisms of response and potential therapeutic directions to modify the inflammatory response and augment the potential for healing.

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More information

Attachments

• Transparency-20211011-Acceptance_ltr.pdf
• Award notice

• Transparency-20210909-Part_C_Task_Response_Form.pdf
• Bid submission documents

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Award information

Awarded date

11 October 2021

Contract start date

12 October 2021

Contract end date

31 August 2022

Total value of contract

£54,992.36

This contract was awarded to 1 supplier.

King's College London

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About the buyer

Address

Porton Down
SALISBURY
SP40JQ
England

Email

cbrcommercial@dstl.gov.uk