Published date: 26 March 2018
Closed opportunity - This means that the contract is currently closed. The buying department may be considering suppliers that have already applied, or no suitable offers were made.
Contract summary
Industry
Laboratory, optical and precision equipments (excl. glasses) - 38000000
Location of contract
South West
Value of contract
£65,000 to £71,000
Procurement reference
20180326130058-53042
Published date
26 March 2018
Closing date
18 April 2018
Contract start date
19 April 2018
Contract end date
20 April 2018
Contract type
Supply contract
Procedure type
Open procedure
Any interested supplier may submit a tender in response to an opportunity notice.
Contract is suitable for SMEs?
Yes
Contract is suitable for VCSEs?
No
Description
Endothelial cell barrier function measurements: Endothelial cells (ECs) play a key role in the cerebrovasculature in maintaining the blood brain barrier (BBB). ECs line the walls of the blood vessels and act as a selective barrier to regulate the passage of fluids, macromolecules, hormones and leukocytes from the vascular space to the interstitium. Our preliminary data indicates that structural alterations of ECs in vitro results in plasma protein leakage and leukocyte extravasation which lead to inflammation.
We have recently received a grant from Alzheimer's Research UK (ARUK) allowing us to invest in a label free, non- invasive and automated instrument that will allow monitoring EC behaviour in real- time.
Essential features of the instrument must include:
• The ability to perform experiments in controlled gas environments in existing incubators
• Cells to be grown on electrodes with multi-well (8, 16 or 96) configuration
• Computer and an integrated software gathering data and analysis (Windows / MAC compatible)
• The ability to measure impedance in a range of frequencies (low to high)
• The ability to perform measurements under flow conditions (to mimic shear stress on ECs in vivo)
• Training, warranty and service contract
• Consumables (10 experiments: 10 x 8 Well Arrays
More information
Links
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- https://uk.eu-supply.com/app/rfq/rwlentrance_s.asp?PID=23734&B=EXETER
- Tender notice
- Applicants need to register their interest on the University of Exeter's electronic tendering System link above. The procurement exercise is completely managed via this system. Registration is free of charge to potential suppliers.
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- https://uk.eu-supply.com/ctm/Company/CompanyInformation/Index/53042
- Tender notice
- To access documents please follow the link above
About the buyer
Contact name
Wendy Herrington
Address
Northcote House
Exeter
EX4 4QH
ENG
Telephone
+44 13926242
Website
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Closing: 18 April 2018
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