Published date: 24 April 2023

Last edited date: 24 April 2023

Closed opportunity - This means that the contract is currently closed. The buying department may be considering suppliers that have already applied, or no suitable offers were made.


Closing: 25 May 2023, 12pm

Contract summary

Industry

  • Laboratory, optical and precision equipments (excl. glasses) - 38000000

  • Industrial process control equipment and remote-control equipment - 38800000

  • Chemical industry machinery - 42993000

Location of contract

M13 9PL

Value of contract

£0

Procurement reference

IT-516-75-2023-2033-BRS-JW-PC

Published date

24 April 2023

Closing date

25 May 2023

Closing time

12pm

Contract start date

19 June 2023

Contract end date

14 February 2024

Contract type

Supply contract

Procedure type

Open procedure (above threshold)

Any interested supplier may submit a tender in response to an opportunity notice.

This procedure can be used for procurements above the relevant contract value threshold.

Contract is suitable for SMEs?

Yes

Contract is suitable for VCSEs?

No

Description

This tender is being run on behalf of Dr James Winterburn, Reader in Chemical Engineering. Dr Winterburn led a successful BBSRC ALERT21 equipment bid "Integrated bioreactor platform for rapid scale-up and translation", which will provide significant bioreactor capacity for microbial fermentation process development, scale up and translation for a range of bio-based chemicals. The exploitation of bio-based production routes requires a thorough understanding of production strain performance and an ability to rapidly and effectively scale processes from millilitres to tens of litres. The bioreactor platform is intended to provide understanding of how process conditions at different volumes and variability across process parameters (e.g., mixing speeds, dissolved O2, pH), affect host cell performance. The integrated bioreactor platform will bridge across three scales, outlined below, and allow for rapid process development and ultimately support research translation.

 Small-scale: Parallel bioreactor system (500 mL, 6 vessels) for rapid parallel process development, strain testing and parameter optimization for microbial fermentations in batch, fed-batch and continuous cultivation, with off gas analysis capability

 Mid-scale (3L bioreactor system, four vessels): For initial scale up and process development work (e.g., confirmation of feeding profiles, metabolic profiling) and preliminary process analysis (including; yield, productivity, final titre) with off gas analysis capability. Also serves as the seed train for inoculum preparation for scale up to 40L.

 Large-scale feasibility (40L SIP bioreactor): To enable in-house demonstration of process technical feasibility, production of sufficient quantities of material for application testing and benchmarking and provision of data for robust techno-economic analysis which can be used as the basis for commercialisation, also with off gas analysis capability.

More information

Links

Additional text

Information, formalities and necessary requirements to be met will be set out in the procurement documents, all of which are available via the University`s procurement portal In-Tend - https://in-tendhost.co.uk/manchesteruniversity


Is a Recurrent Procurement Type? : No

About the buyer

Contact name

Paul Carter

Address

Manchester
Manchester
Manchester
M13 9PL
United Kingdom

Telephone

-

Email

paul.carter-2@manchester.ac.uk