Published date: 31 October 2023

Closed opportunity - This means that the contract is currently closed. The buying department may be considering suppliers that have already applied, or no suitable offers were made.


Closing: 30 November 2023, 12pm

Contract summary

Industry

  • Laboratory, optical and precision equipments (excl. glasses) - 38000000

Location of contract

B15 2TT

Value of contract

£0 to £550,000

Procurement reference

SC12074/23

Published date

31 October 2023

Closing date

30 November 2023

Closing time

12pm

Contract start date

7 January 2024

Contract end date

31 March 2024

Contract type

Supply contract

Procedure type

Open procedure (above threshold)

Any interested supplier may submit a tender in response to an opportunity notice.

This procedure can be used for procurements above the relevant contract value threshold.

Contract is suitable for SMEs?

Yes

Contract is suitable for VCSEs?

No

Description

The University of Birmingham invites tenders for supply of a in-vivo radiation research platform (SARRP) capable of delivering X-ray irradiation at both conventional (~2-5 Gy/min) and ultra-high dose rates (FLASH; >40 Gy/sec). The system is required for both cultured cells (e.g. immortalised cell lines, primary cell cultures, 3D spheroids/organoids) as well as in-vivo models. The system will be used in scientific research to explore the biological impact of X-ray irradiation delivered at FLASH dose rates, particularly in terms of cell survival, growth of tumors, and impact on critical cellular structures such as DNA. This research spanning cancer, molecular and cellular biology aims to contribute to our further understanding of FLASH radiation, and to move this towards the clinic for the benefit of cancer patients treated with radiotherapy.

The system must be capable of delivering X-ray irradiation at FLASH dose rates (>40 Gy/sec) and be integrated within a shielded cabinet that is safe to use. Accurate and real-time dosimetry is very important. The system should have a stage which is manoeuvrable in three directions (X, Y and Z) plus a user-friendly and computer interface for precise cell positioning, but also come complete with a CCD camera for sample focusing and real-time monitoring. Continuing support in the maintenance and accuracy of dose delivery of the equipment is essential.

Please refer to Appendix A for full specification of requirements via In-tend - www.intendhost.com/universityofbirmingham

About the buyer

Contact name

Kseniya Samsonik

Address

University of Birmingham
BIRMINGHAM
B152TT
England

Email

k.samsonik@bham.ac.uk